ACTICLOT® Protein C Resistance

Product Description

Plasma based functional assay for the determination of resistance to activated protein C caused by the factor V Leiden mutation (FV:Q506). Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. Over 95% of the APC resistance phenotype can be explained by the Factor V Leiden mutation. This defect is caused by point mutation in the factor V gene resulting in a replacement of the amino acid Arg 506 by a Gln residue. The heterozygous defect is associated with a 5 to 10 fold, the homozygous defect with a 50 to 100 fold increased thrombosis risk.

For in-vitro diagnostic use.

ACTICLOT® Activated Protein C Resistance Kit 840 120


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