Recombinant Human Tissue Factor

Product Description

Tissue Factor (TF) is a 45 kD transmembrane cell surface glycoprotein known for its role in initiating coagulation. TF is comprised of three domains: an extracellular domain (aa 1-219), followed by a hydrophilic spanning domain (aa 220-242) and a cytoplasmic tail (aa 243-263). It functions as a receptor and cofactor for the latent serine proteases factor VII and VIIa. Contact between TF and blood is sufficient to initiate the extrinsic pathway of coagulation.

Recombinant Human Tissue Factor 4500 25 µg


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